Testicular cancer seminoma is one of the most common types of cancer among men of reproductive age. Patients with this condition usually present reduced semen quality, even before initiating cancer therapy. However, the underlying mechanisms by which testicular cancer seminoma affects male fertility are largely unknown. The aim of this study was to investigate alterations in the sperm proteome of men with seminoma undergoing sperm banking before starting cancer therapy, in comparison to healthy proven fertile men control group.
Semen quality from patients affected by seminomatous and non-seminomatous testicular tumor
Treatment for testicular cancer does not affect your ability to have sex but it may affect your fertility or reduce your sex drive. This is usually temporary. It is normal to worry about the possible effects of testicular cancer and its treatment on your sex life and fertility. Fertility is being able to make someone pregnant.
Fertility and Hormone Concerns in Boys and Men With Testicular Cancer
In a study of men with testicular cancer, increasing tumor size relative to testis size was linked with a reduced ability to produce sperm. The study included men with testicular cancer. The rule of 50s can help guide patients and clinicians at diagnosis regarding fertility counselling and treatment, including referral of patients with no sperm in their ejaculate for onco-microTESE, which involves surgical sperm retrieval from the affected testicle at the time of cancer surgery. Materials provided by Wiley.
It is a largely curable disease, so the extent to which it affects quality of life—including male fertility—is important. Abnormal semen analysis is highly predictive of male infertility. We conducted a systematic review of published studies that reported pre-orchiectomy semen parameters as a surrogate for fertility in TGCT patients to evaluate the association between TGCT and semen abnormalities before orchiectomy. Methods: We conducted a systematic review of peer-reviewed publications reporting semen parameters before orchiectomy in adult patients diagnosed with TGCT.