Jump to content. An antisperm antibody test looks for special proteins antibodies that fight against a man's sperm in blood, vaginal fluids, or semen. The test uses a sample of sperm and adds a substance that binds only to affected sperm. Semen can cause an immune system response in either the man's or woman's body.
Antisperm Antibody Test | Michigan Medicine
Antisperm antibodies are antibodies produced against sperm antigens. ASA can be detected in ejaculate, cervical mucus, follicular fluid, and blood serum of both males and females. IgG occurring in genital tract fluids is either produced locally or transuded from blood serum, whereas IgA secretory type is always produced locally. ASA can arise whenever sperm encounter the immune system. However, these antibodies are also present in approximately 1—2. Different tests have been developed to identify ASA in various biological substrates. MAR test in its original version is based on the classical Coombs test — sperm is mixed with human red blood cells coated with human IgG.
Antisperm Antibody Test
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